INSERM UMR-S 864, Espace et Action, Université Lyon I, Hospices Civils de Lyon, hôpital neurologique, service de neurologie D et unité de neuro-ophtalmologie, BRON Cedex, France.
J Neuroophthalmol. 2011 Mar;31(1):38-41. doi: 10.1097/WNO.0b013e3181f8dc23.
Two unusual cases of monocular pendular nystagmus in patients with multiple sclerosis are reported. One patient showed regular horizontal oscillations of the right eye in abduction, associated with right abduction paresis. The second patient had a similar abnormal eye movement of the left eye in adduction, with partial left internuclear ophthalmoplegia. Such eye position-dependent monocular pendular nystagmus provides new insights into pathogenic mechanism for acquired pendular nystagmus. Different mechanisms are discussed such as the combination of paresis and commonly accepted hypothesis of dysfunction of visual and/or motor feedback loops in the ocular motor neural network.
报告了 2 例多发性硬化症患者单眼摆动性眼球震颤的不寻常病例。一名患者在右眼外展时出现规则的水平摆动，伴有右眼外展无力。第二位患者左眼内收时出现类似的异常眼球运动，伴有部分左眼核间眼肌麻痹。这种依赖眼球位置的单眼摆动性眼球震颤为获得性摆动性眼球震颤的发病机制提供了新的见解。讨论了不同的机制，例如无力与视觉和/或运动反馈回路功能障碍的常见假设在眼球运动神经网络中的结合。
