Li Tuo, He Tao, Tan Xiaodong, Yang Shurong, Li Jiazhang, Peng Zuoquan, Li Hongyan, Song Xiusheng, Wu Qingsong, Yang Fanglie, Xing Yiqiao
Department of Ophthalmology, Renmin Hospital of Wuhan University, 238 Jiefang Road, Wuhan, Hubei Province, China.
Biol Trace Elem Res. 2009 Apr;128(1):1-7. doi: 10.1007/s12011-008-8248-y. Epub 2008 Oct 30.
The objective of this study was to determine the prevalence of age-related cataract in high-selenium areas of China. This is a cross-sectional study of 1,522 persons aged 50 years and more who were selected as a representative sample from the Enshi prefecture in Hubei province. All lenses were graded and classified for opacities by slit lamp after papillary dilation, using the Lens Opacification Classification System II. The age-related cataract patients were 418 cases (33.28%). The prevalence of age-related cataract was 37.2% in women and 26.0% in men. The prevalence of nuclear cataract was 23.7%; cortical cataract was 22.4% and posterior subcapsule cataract was 5.2%. The prevalence of cataract of the 50-59 group was 13.41%; 60-69 group was 42.15%; 70 and over group was 61.9%. The prevalence of age-related cataract in high-selenium areas has not significantly increased; to some extent, the high selenium intake will not become a risk factor for the increase of cataract incidence.
本研究的目的是确定中国高硒地区年龄相关性白内障的患病率。这是一项横断面研究，从湖北省恩施州选取了1522名50岁及以上的人员作为代表性样本。在瞳孔散大后，使用晶状体混浊分级系统II，通过裂隙灯对所有晶状体的混浊情况进行分级和分类。年龄相关性白内障患者有418例（33.28%）。年龄相关性白内障的患病率在女性中为37.2%，在男性中为26.0%。核性白内障的患病率为23.7%；皮质性白内障为22.4%，后囊下白内障为5.2%。50 - 59岁组白内障的患病率为13.41%；60 - 69岁组为42.15%；70岁及以上组为61.9%。高硒地区年龄相关性白内障的患病率没有显著增加；在一定程度上，高硒摄入不会成为白内障发病率增加的危险因素。
