Fahmy K, el-Gazar A, Eisa I, Ghonaim M, Saad S, Afifi A
Department of Obstetrics and Gynecology, Benha, Egypt.
Gynecol Endocrinol. 1991 Mar;5(1):1-5. doi: 10.3109/09513599109049936.
Serum progesterone, estradiol, testosterone and cortisol were assayed in the mid-follicular and mid-luteal phases of the menstrual cycles in 30 Lippe's loop and 30 Cu T-200 IUCD users, compared to 24 controls. Mean serum progesterone and estradiol levels were significantly higher in the mid-luteal, compared to the mid-follicular phase in each group (p less than 0.01). There were no significant differences between the mean levels of progesterone, testosterone and cortisol in IUCD users and controls in both the mid-follicular and mid-luteal phases. IUCD users had significantly higher levels of estradiol (p less than 0.01) in the mid-luteal phase but not in the mid-follicular phase, compared to controls. There was hormonal evidence of corpus luteum insufficiency in 8.3%, 14.3% and 20% in the controls, Lippe's loop and Cu T-200 IUCD users, respectively.
对30名使用利普氏节育环（Lippe's loop）和30名使用铜T - 200宫内节育器（Cu T - 200 IUCD）的女性以及24名对照者，在月经周期的卵泡中期和黄体中期测定血清孕酮、雌二醇、睾酮和皮质醇水平。与卵泡中期相比，每组黄体中期的血清孕酮和雌二醇平均水平显著更高（p小于0.01）。在卵泡中期和黄体中期，宫内节育器使用者与对照者的孕酮、睾酮和皮质醇平均水平均无显著差异。与对照者相比，宫内节育器使用者在黄体中期的雌二醇水平显著更高（p小于0.01），但在卵泡中期并非如此。对照者、使用利普氏节育环者和使用铜T - 200宫内节育器者中黄体功能不全的激素证据分别为8.3%、14.3%和20%。
