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在三级转诊中心进行的腹腔镜保留生育功能的深部浸润性盆腔子宫内膜异位症切除术的短期疗效。

Short-term outcome of fertility-sparing laparoscopic excision of deeply infiltrating pelvic endometriosis performed in a tertiary referral center.

机构信息

Institute of Women's Health, University College London Hospitals, London, United Kingdom.

出版信息

Fertil Steril. 2010 Jan;93(1):39-45. doi: 10.1016/j.fertnstert.2008.09.051. Epub 2008 Oct 29.

Abstract

OBJECTIVE

To examine the short-term surgical outcomes in women undergoing fertility-sparing laparoscopic excision of deeply infiltrating pelvic endometriosis.

DESIGN

Retrospective cohort study.

SETTING

Tertiary referral center for treatment of endometriosis, a university teaching hospital, London, United Kingdom.

PATIENT(S): A total of 177 women who underwent fertility-sparing laparoscopic excision of deeply infiltrating endometriosis between January 1, 2006, and December 31, 2007.

INTERVENTION(S): Eligible women were identified from the surgeons' database, and their medical notes were reviewed. Data from preoperative assessment, surgery, and postoperative outcomes were analyzed.

MAIN OUTCOME MEASURE(S): Complication rate.

RESULT(S): One hundred seventy-seven women underwent fertility-sparing laparoscopic excision of deeply infiltrating endometriosis including excision of uterosacral ligaments (43, 24.3%), excision of rectovaginal septum (56, 31.6%), rectal shave (56, 31.6%), disk excision (7, 4%) or bowel resection (15, 8.5%). The median operative time was 95 minutes with a range of 30 to 270 minutes (interquartile range 75-120 minutes). Overall, complications developed in 18 women (10.2%). In 12 (6.8%) of these only uncomplicated pyrexia developed whereas significant intraoperative and/or postoperative complications developed in the remaining 6 (3.4%). Women spent a median of 2 days recovering in hospital (range 1-7, interquartile range 2-3 days).

CONCLUSION(S): Fertility-sparing laparoscopic excision of deeply infiltrating endometriosis appears to be safe with a low short-term complication rate.

摘要

目的

研究行保留生育功能的腹腔镜深部浸润型子宫内膜异位症切除术的短期手术结局。

设计

回顾性队列研究。

地点

英国伦敦一所大学附属医院,三级转诊中心治疗子宫内膜异位症。

患者

2006 年 1 月 1 日至 2007 年 12 月 31 日期间,共 177 例行保留生育功能的腹腔镜深部浸润型子宫内膜异位症切除术的患者。

干预

从外科医生的数据库中确定符合条件的患者,并对其病历进行回顾性分析。分析术前评估、手术和术后结果的数据。

主要观察指标

并发症发生率。

结果

177 例行保留生育功能的腹腔镜深部浸润型子宫内膜异位症切除术的患者,包括切除子宫骶骨韧带(43 例,24.3%)、直肠阴道隔(56 例,31.6%)、直肠刮除术(56 例,31.6%)、椎间盘切除术(7 例,4%)或肠切除术(15 例,8.5%)。中位手术时间为 95 分钟,范围 30 至 270 分钟(四分位间距 75-120 分钟)。总体而言,18 例(10.2%)患者出现并发症。其中 12 例(6.8%)仅出现单纯发热,而其余 6 例(3.4%)出现明显的术中及/或术后并发症。患者平均住院 2 天(范围 1-7 天,四分位间距 2-3 天)恢复。

结论

行保留生育功能的腹腔镜深部浸润型子宫内膜异位症切除术安全性高,短期并发症发生率低。

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