束状韧黑伞中过氧化麦角甾醇的抗补体活性及核磁共振数据的重新归属
Anticomplementary activity of ergosterol peroxide fromNaematoloma fasciculare and reassignment of NMR data.
作者信息
Kim D S, Baek N I, Oh S R, Jung K Y, Lee I S, Kim J H, Lee H K
机构信息
Korea Research Institute of Bioscience & Biotechnology, KIST, Yusong P.O. Box 115, 305-600, Taejon, Korea.
出版信息
Arch Pharm Res. 1997 Jun;20(3):201-5. doi: 10.1007/BF02976145.
A very high content (at least 0.23%) of ergosterol peroxide was isolated fromNaematoloma fasciculare Karst. Not only ergosterol peroxide but also ergosterol showed very strong anticomplementary activity on the classical pathway, the IC(50) values being 5.0 muM and 1.0 muM, respectively. The(1)H and(13)C NMR data of ergosterol peroxide were revised and completely assigned by DEPT,(1)H-(1)H COSY, HMQC and HMBC correlations.
从束状黑伞（Naematoloma fasciculare Karst.）中分离出了含量非常高（至少0.23%）的过氧化麦角甾醇。过氧化麦角甾醇和麦角甾醇在经典途径上均表现出非常强的抗补体活性，IC(50)值分别为5.0 μM和1.0 μM。通过DEPT、(1)H-(1)H COSY、HMQC和HMBC相关对过氧化麦角甾醇的(1)H和(13)C NMR数据进行了修订并完全归属。
Zotero 插件