Zisook S, Shuchter S R
University of California, Department of Psychiatry, San Diego.
Am J Psychiatry. 1991 Oct;148(10):1346-52. doi: 10.1176/ajp.148.10.1346.
This study assesses the frequency of depressive syndromes during the first 13 months after the death of a spouse.
Men and women whose spouses had recently died were identified through death certificate records. These subjects completed a multidimensional questionnaire and were interviewed 7-8 weeks (2 months) after the death. Follow-up questionnaires were completed 7 and 13 months after the death. The questionnaires contained specific items corresponding to DSM-III-R criteria for depressive episodes as well as other widely used measures of depressive symptoms such as the Zung Depression Scale and the Hopkins Symptom Checklist.
Eighty-four (24%) of 350 widows and widowers met criteria for depressive episodes at 2 months, 72 (23%) of 308 did so at 7 months, and 46 (16%) of 286 did so at 13 months. At each time period, the prevalence was substantially higher than the 4% rate of depressive episodes observed in a comparison group of 126 subjects whose spouses were still living. Widows and widowers most likely to meet criteria for depressive episodes 13 months after the bereavement were younger, had past histories of major depression, were still grieving 2 months after the loss, and met DSM-III-R criteria for depressive episodes 2 and/or 7 months after the death.
Depressive episodes are common after the death of a spouse. Clinicians should maintain a high index of suspicion for the possibility of depression, particularly in young widows and widowers who have a past history of depression or who experience a full depressive syndrome soon after the loss.
本研究评估配偶死亡后头13个月内抑郁综合征的发生频率。
通过死亡证明记录确定配偶近期死亡的男性和女性。这些受试者完成了一份多维度问卷,并在死亡后7 - 8周(2个月)接受访谈。在死亡后7个月和13个月完成随访问卷。问卷包含与DSM - III - R抑郁发作标准相对应的特定项目,以及其他广泛使用的抑郁症状测量工具,如zung抑郁量表和霍普金斯症状清单。
350名鳏夫寡妇中,84人(24%)在2个月时符合抑郁发作标准,308人中有72人(23%)在7个月时符合,286人中有46人(16%)在13个月时符合。在每个时间段,患病率均显著高于126名配偶仍在世的对照组中观察到的4%的抑郁发作率。在丧亲后13个月最有可能符合抑郁发作标准的鳏夫寡妇年龄较小,有重度抑郁病史,在失去亲人2个月后仍处于悲痛中,且在死亡后2个月和/或7个月符合DSM - III - R抑郁发作标准。
配偶死亡后抑郁发作很常见。临床医生应高度怀疑抑郁的可能性,尤其是对于有抑郁病史或在失去亲人后不久出现完全抑郁综合征的年轻鳏夫寡妇。