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1993 - 2005年慢性阻塞性肺疾病急性加重期急诊就诊情况的全国性研究

National study of emergency department visits for acute exacerbation of chronic obstructive pulmonary disease, 1993-2005.

作者信息

Tsai Chu-Lin, Sobrino Justin A, Camargo Carlos A

机构信息

Department of Emergency Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.

出版信息

Acad Emerg Med. 2008 Dec;15(12):1275-83. doi: 10.1111/j.1553-2712.2008.00284.x. Epub 2008 Oct 25.

Abstract

OBJECTIVES

Little is known about recent trends in U.S. emergency department (ED) visits for acute exacerbation of chronic obstructive pulmonary disease (AECOPD) or about ED management of AECOPD. This study aimed to describe the epidemiology of ED visits for AECOPD and to evaluate concordance with guideline-recommended care.

METHODS

Data were obtained from National Hospital Ambulatory Medical Care Survey (NHAMCS). ED visits for AECOPD, during 1993 to 2005, were identified using the International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM) codes. Concordance with guideline recommendations was evaluated using process measures.

RESULTS

Over the 13-year study period, there was an average annual 0.6 million ED visits for AECOPD, and the visit rates for AECOPD were consistently high (3.2 per 1,000 U.S. population; P(trend) = 0.13). The trends in the use of chest radiograph, pulse oximetry, or bronchodilator remained stable (all P(trend) > 0.5). By contrast, the use of systemic corticosteroids increased from 29% in 1993-1994 to 60% in 2005, antibiotics increased from 14% to 42%, and methylxanthines decreased from 15% to <1% (all P(trend) < 0.001). Multivariable analysis showed patients in the South (vs. the Northeast) were less likely to receive systemic corticosteroids (odds ratio [OR] = 0.6; 95% confidence interval [CI] = 0.4 to 0.9).

CONCLUSIONS

The high burden of ED visits for AECOPD persisted. Overall concordance with guideline-recommended care for AECOPD was moderate, and some emergency treatments had improved over time.

摘要

目的

对于美国急诊科(ED)因慢性阻塞性肺疾病急性加重(AECOPD)就诊的近期趋势以及AECOPD的急诊科管理了解甚少。本研究旨在描述AECOPD的急诊科就诊流行病学,并评估与指南推荐治疗的一致性。

方法

数据来自国家医院门诊医疗调查(NHAMCS)。使用国际疾病分类第九版临床修订本(ICD-9-CM)编码确定1993年至2005年期间因AECOPD的急诊科就诊情况。使用过程指标评估与指南推荐的一致性。

结果

在13年的研究期间,每年平均有60万例因AECOPD的急诊科就诊,且AECOPD的就诊率一直很高(每1000名美国人口中有3.2例;P(趋势)=0.13)。胸部X线检查、脉搏血氧饱和度测定或支气管扩张剂的使用趋势保持稳定(所有P(趋势)>0.5)。相比之下,全身用糖皮质激素的使用从1993 - 1994年的29%增至2005年的60%,抗生素从14%增至42%,而黄嘌呤类药物从15%降至<1%(所有P(趋势)<0.001)。多变量分析显示,南部地区(与东北部地区相比)的患者接受全身用糖皮质激素的可能性较小(比值比[OR]=0.6;95%置信区间[CI]=0.4至0.9)。

结论

因AECOPD的急诊科就诊负担依然很高。总体而言,与AECOPD指南推荐治疗的一致性为中等,且一些急诊治疗随时间有所改善。

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