吉普赛内源性逆转录病毒在几种果蝇物种中保持潜在感染性。
Gypsy endogenous retrovirus maintains potential infectivity in several species of Drosophilids.
作者信息
Llorens Jose V, Clark Jonathan B, Martínez-Garay Isabel, Soriano Sirena, de Frutos Rosa, Martínez-Sebastián María J
机构信息
Departament de Genètica, Universitat de València, 46100-Burjassot, Valencia, Spain.
出版信息
BMC Evol Biol. 2008 Oct 31;8:302. doi: 10.1186/1471-2148-8-302.
BACKGROUND
Sequences homologous to the gypsy retroelement from Drosophila melanogaster are widely distributed among drosophilids. The structure of gypsy includes an open reading frame resembling the retroviral gene env, which is responsible for the infectious properties of retroviruses.
RESULTS
In this study we report molecular and phylogeny analysis of the complete env gene from ten species of the obscura group of the genus Drosophila and one species from the genus Scaptomyza.
CONCLUSION
The results indicate that in most cases env sequences could produce a functional Env protein and therefore maintain the infectious capability of gypsy in these species.
背景
与黑腹果蝇的吉普赛反转录元件同源的序列广泛分布于果蝇科昆虫中。吉普赛元件的结构包含一个类似于逆转录病毒基因env的开放阅读框，该基因负责逆转录病毒的感染特性。
结果
在本研究中，我们报告了果蝇属蒙胧果蝇组十个物种和黑腹果蝇属一个物种的完整env基因的分子和系统发育分析。
结论
结果表明，在大多数情况下，env序列可以产生功能性Env蛋白，因此在这些物种中维持吉普赛元件的感染能力。
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