Ludwig A, Valente V L da S, Loreto E L S
Programa de Pós-Graduação em Genética e Biologia Molecular, Departamento de Genética, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, Rio Grande do Sul, Brazil.
Insect Mol Biol. 2008 Apr;17(2):113-24. doi: 10.1111/j.1365-2583.2007.00787.x.
Aiming to contribute to the knowledge of the evolutionary history of Errantivirus, a phylogenetic analysis of the env gene sequences of Errantivirus gypsy, gtwin, gypsy2, gypsy3, gypsy4 and gypsy6 was carried out in 33 Drosophilidae species. Most sequences were obtained from in silico searches in the Drosophila genomes. The complex evolutionary pattern reported by other authors for the gypsy retroelement was also observed in the present study, including vertical transmission, ancestral polymorphism, stochastic loss and horizontal transfer. Moreover, the elements gypsy2, gypsy3, gypsy4 and gypsy6 were shown to have followed an evolutionary model that is similar to gypsy. Fifteen new possible cases of horizontal transfer were suggested. The infectious potential of these elements may help elucidate the evolutionary scenario described in the present study.
为了增进对Errantivirus进化历史的了解，在33种果蝇科物种中对Errantivirus gypsy、gtwin、gypsy2、gypsy3、gypsy4和gypsy6的env基因序列进行了系统发育分析。大多数序列是通过对果蝇基因组的电子搜索获得的。本研究还观察到了其他作者报道的gypsy反转录元件的复杂进化模式，包括垂直传播、祖先多态性、随机丢失和水平转移。此外，gypsy2、gypsy3、gypsy4和gypsy6元件显示出遵循与gypsy相似的进化模式。提出了15个新的可能的水平转移案例。这些元件的感染潜力可能有助于阐明本研究中描述的进化情况。
