Oeltmann John E, Varma Jay K, Ortega Luis, Liu Yecai, O'Rourke Thomas, Cano Maria, Harrington Theresa, Toney Sean, Jones Warren, Karuchit Samart, Diem Lois, Rienthong Dhanida, Tappero Jordan W, Ijaz Kashef, Maloney Susan A
Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA.
Emerg Infect Dis. 2008 Nov;14(11):1715-21. doi: 10.3201/eid1411.071629.
In January 2005, tuberculosis (TB), including multidrug-resistant TB (MDR TB), was reported among Hmong refugees who were living in or had recently immigrated to the United States from a camp in Thailand. We investigated TB and drug resistance, enhanced TB screenings, and expanded treatment capacity in the camp. In February 2005, 272 patients with TB (24 MDR TB) remained in the camp. Among 17 MDR TB patients interviewed, 13 were found to be linked socially. Of 23 MDR TB isolates genotyped, 20 were similar according to 3 molecular typing methods. Before enhanced screening was implemented, 46 TB cases (6 MDR TB) were diagnosed in the United States among 9,455 resettled refugees. After enhanced screening had begun, only 4 TB cases (1 MDR TB), were found among 5,705 resettled refugees. An MDR TB outbreak among US-bound refugees led to importation of disease; enhanced pre-immigration TB screening and treatment decreased subsequent importation.
2005年1月，在居住于泰国某难民营或刚从该难民营移民至美国的苗族难民中报告了结核病（TB），包括耐多药结核病（MDR TB）。我们对该难民营中的结核病及耐药情况进行了调查，加强了结核病筛查，并扩大了治疗能力。2005年2月，仍有272例结核病患者（24例耐多药结核病患者）留在该难民营。在接受访谈的17例耐多药结核病患者中，发现有13例存在社会关联。在对23株耐多药结核分枝杆菌分离株进行基因分型后，根据3种分子分型方法，其中20株相似。在加强筛查实施之前，在美国重新安置的9455名难民中诊断出46例结核病病例（6例耐多药结核病病例）。加强筛查开始后，在5705名重新安置的难民中仅发现4例结核病病例（1例耐多药结核病病例）。前往美国的难民中发生的耐多药结核病疫情导致了疾病的输入；加强移民前的结核病筛查和治疗减少了随后的疾病输入。
