Gregory Jennifer S, Aspden Richard M
Bone and Musculoskeletal Programme, Division of Applied Medicine, University of Aberdeen, UK.
Med Eng Phys. 2008 Dec;30(10):1275-86. doi: 10.1016/j.medengphy.2008.09.002. Epub 2008 Oct 31.
Osteoporotic hip fracture is associated with high mortality and morbidity and often results in a loss of mobility and independence. Osteoporosis is diagnosed by measuring Bone Mineral Density (BMD), a measure of the amount of mineral in a bone. Although BMD continues to serve well it does not fully account for bone strength and only partially accounts for the risk of hip fracture. The shape and structure of the proximal femur also help to determine how forces act in the hip in a fall and their measurement can aid the prediction of hip fracture. This review examines the link between simple geometrical measures of the proximal femur and hip fracture, or bone strength. It will explore how they relate to each other and to anthropometric factors such as sex, height, weight and age. Limitations in these measures will be identified and new methods of analysis reviewed that encompass many different aspects of the shape of the femur. These new methods show great promise for improving the prediction of fracture risk in the future.
骨质疏松性髋部骨折与高死亡率和高发病率相关,常导致行动能力和独立性丧失。骨质疏松症通过测量骨密度(BMD)来诊断,骨密度是衡量骨骼中矿物质含量的指标。尽管骨密度仍然很有用,但它并不能完全反映骨骼强度,只能部分解释髋部骨折的风险。股骨近端的形状和结构也有助于确定跌倒时髋部受力的方式,对其进行测量有助于预测髋部骨折。本综述探讨了股骨近端简单几何测量与髋部骨折或骨骼强度之间的联系。它将探究它们彼此之间以及与性别、身高、体重和年龄等人体测量因素之间的关系。将确定这些测量方法的局限性,并对涵盖股骨形状许多不同方面的新分析方法进行综述。这些新方法在未来改善骨折风险预测方面显示出巨大潜力。