Senkowski A, Colonna M, Bicout D-J
Laboratoire EPSP-TIMC, faculté de médecine, Domaine de la Merci, 38700 La Tronche, France.
Rev Epidemiol Sante Publique. 2008 Oct;56(5):315-21. doi: 10.1016/j.respe.2008.06.259. Epub 2008 Oct 31.
Mapping a Cancer Atlas for the urban area of Grenoble revealed spatial distribution in the incidence of lung cancer among males at municipality level. Thus, our goal in this work was to use a new finer spatial scale to find out whether or not observed spatial variations might mask intramunicipality spatial variations.
The use of a Bayesian smoothing approach allowed us to overcome problems related to the very small inframunicipality scale and to take into account the spatial autocorrelation existing between neighbouring units. The relative risks were adjusted on different socioeconomic variables like the median income per consumption unit.
After smoothing, areas with statistically significant 30 to 40% excess of cases and lack of cases were identified within the urban area of Grenoble. Median income per consumption unit appeared to be the most discriminating variable for characterizing the studied population.
The inframunicipality scale enables the study of a health problem as the lung cancer within a context of strong demographic disparities.
绘制格勒诺布尔市区的癌症地图揭示了市镇层面男性肺癌发病率的空间分布。因此,我们这项工作的目标是使用一个新的更精细的空间尺度,以查明观察到的空间差异是否可能掩盖了市辖区内的空间差异。
使用贝叶斯平滑方法使我们能够克服与市辖区内非常小的尺度相关的问题,并考虑相邻单元之间存在的空间自相关性。相对风险根据不同的社会经济变量进行了调整,如每个消费单位的中位数收入。
平滑后,在格勒诺布尔市区内确定了病例数有统计学显著增加30%至40%的区域以及病例数不足的区域。每个消费单位的中位数收入似乎是表征所研究人群最具区分性的变量。
市辖区内尺度能够在人口差异较大的背景下研究肺癌等健康问题。