Shimeliovich I L, Lanskaia I M, Andrianova M Iu, Lur'e G O, Mal'tseva A Iu
Anesteziol Reanimatol. 1991 May-Jun(3):32-6.
Changes in the concentration of calcium and its fractions have been studied in 115 patients subject to standard bypass techniques. It has been found that calcium homeostasis disturbances do really develop and are caused by the use of solutions that are not balanced with blood in their calcium content. The main source of calcium in hemodiluents was gelatinol. A decrease in gelatinol volume to 450-600 ml prevented the onset of marked hypercalcemia. As ionized calcium (Ca2+) concentration is determined not only by the total Ca level, but also by the shifts in the degree of pH- and pCO2-dependent ionization and binding and in ligand and protein content, Ca2+ determination is considered an optimal method of calcium homeostasis control during cardiopulmonary bypass.
对115例接受标准搭桥技术的患者的钙浓度及其组分变化进行了研究。已发现钙稳态紊乱确实会发生，并且是由使用钙含量与血液不平衡的溶液引起的。血液稀释剂中钙的主要来源是明胶醇。将明胶醇的用量减少至450 - 600毫升可防止明显高钙血症的发生。由于离子钙（Ca2+）浓度不仅取决于总钙水平，还取决于pH值和pCO2依赖性电离和结合程度以及配体和蛋白质含量的变化，因此Ca2+测定被认为是体外循环期间钙稳态控制的最佳方法。
