Shimeliovich I L, Andrianova M Iu, Lur'e G O, Mal'tseva A Iu
Anesteziol Reanimatol. 1991 Mar-Apr(2):15-7.
Total calcium (CaT) and total magnesium (MgT) levels have been determined in 21 solutions used in cardiopulmonary bypass surgery and manufactured in the USSR. It has been found that a great number of solutions differ in CaT content from human plasma. Some solutions contain Ca, which is not required by the prescription. Even in one and the same lot solutions vary greatly in Ca content (gelatinol). A large number of the solutions tested does not correspond to blood in MgT content, either. Like Ca, this parameter is quite unstable. Such differences in CaT and MgT levels practically in all standard Soviet-made solutions make it impossible to determine accurately precise amount of the solution required. The optimal way of hypercalcemia and hypermagnesiuemia prevention is the elaboration of the solutions identical to blood in their Ca and Mg content, or the use of colloids, practically free of electrolytes (hexaethyl starch).
已对苏联制造的21种用于体外循环手术的溶液中的总钙(CaT)和总镁(MgT)水平进行了测定。结果发现,许多溶液的CaT含量与人体血浆不同。有些溶液含有处方中未要求的钙。即使在同一批次的溶液中,钙含量(明胶醇)也有很大差异。大量测试的溶液在MgT含量上也与血液不符。与钙一样,这个参数也相当不稳定。几乎所有苏联制造的标准溶液中CaT和MgT水平的这种差异使得无法准确确定所需溶液的精确量。预防高钙血症和高镁血症的最佳方法是研制钙和镁含量与血液相同的溶液,或者使用几乎不含电解质的胶体(六乙基淀粉)。