De Rycke J
INRA, Station de pathologie infectieuse et d'immunologie, Nouzilly, France.
Ann Rech Vet. 1991;22(2):105-26.
This article reviews published data (October 1st, 1990) on 4 types of cytotoxins produced by animal and human pathogenic strains of E coli, ie, verotoxins, also named Shiga-like toxins, cytotoxic necrotizing factors, haemolysin, and cytolethal distending toxin. The biological and molecular properties are described for each type of cytotoxin, the association of producing strains with animal pathology, and the role of domestic animals as reservoirs of strains pathogenic for man.
本文综述了已发表的数据(1990年10月1日),内容涉及大肠杆菌动物和人类致病菌株产生的4种细胞毒素,即维罗毒素(也称为志贺样毒素)、细胞毒性坏死因子、溶血素和细胞致死性膨胀毒素。文中描述了每种细胞毒素的生物学和分子特性、产毒菌株与动物病理学的关联,以及家畜作为人类致病菌株储存宿主的作用。