从腹泻羔羊和山羊幼崽中分离出的大肠杆菌菌株对14种抗菌药物的体外敏感性。
In vitro susceptibility of Escherichia coli strains isolated from diarrhoeic lambs and goat kids to 14 antimicrobial agents.
作者信息
Cid D, Píriz S, Ruiz-Santa-Quiteria J A, Valle J, Vadillo S, de la Fuente R
机构信息
Departamento Patología Animal I, Facultad de Veterinaria, Universidad Complutense, Madrid Spain.
出版信息
J Vet Pharmacol Ther. 1996 Oct;19(5):397-401. doi: 10.1111/j.1365-2885.1996.tb00070.x.
Abstract
The in vitro activities of 14 anti-microbial agents were determined against 92 strains of E. coli isolated from lambs (60 strains) and kids (32 strains) affected by neonatal diarrhoea. The overall percentage of resistant strains to streptomycin, sulphadimethoxine and tetracycline was very high (above 70%). A high level of resistance (from 30% to 50%) to ampicillin, kanamycin, neomycin and chloramphenicol was also detected. The E. coli strains were highly susceptible to cephalosporins, polymyxin and quinolones. Most of the strains showed multiresistance: 77.2% of isolates were resistant to at least two antibiotics, 55.4% were resistant to at least four antibiotics and 33.7% were resistant to at least six antibiotics. A total of 34 antibiotypes could be distinguished.
摘要
测定了14种抗菌剂对从患新生儿腹泻的羔羊（60株）和幼羊（32株）分离出的92株大肠杆菌的体外活性。对链霉素、磺胺二甲氧嘧啶和四环素的耐药菌株总体百分比非常高（超过70%）。还检测到对氨苄西林、卡那霉素、新霉素和氯霉素的高耐药水平（30%至50%）。大肠杆菌菌株对头孢菌素、多粘菌素和喹诺酮类高度敏感。大多数菌株表现出多重耐药性：77.2%的分离株对至少两种抗生素耐药，55.4%对至少四种抗生素耐药，33.7%对至少六种抗生素耐药。总共可区分出34种抗菌型。
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