James Anthony A
Department of Molecular Biology and Biochemistry, University of California, Irvine, USA.
J Vis Exp. 2007(5):231. doi: 10.3791/231. Epub 2007 Jul 4.
In this candid interview, Anthony A. James explains how mosquito genetics can be exploited to control malaria and dengue transmission. Population replacement strategy, the idea that transgenic mosquitoes can be released into the wild to control disease transmission, is introduced, as well as the concept of genetic drive and the design criterion for an effective genetic drive system. The ethical considerations of releasing genetically-modified organisms into the wild are also discussed.
在这次坦诚的采访中，安东尼·A·詹姆斯解释了如何利用蚊子遗传学来控制疟疾和登革热传播。文中介绍了种群替代策略，即可以将转基因蚊子释放到野外以控制疾病传播的理念，还提到了基因驱动的概念以及有效基因驱动系统的设计标准。此外，也讨论了向野外释放转基因生物的伦理考量。
