Kessler M, Kandel-Tschiederer B, Pfleghaar S, Tassani-Prell M
Tierärztliche Klinik für Kleintiere, Hofheim, Germany.
Schweiz Arch Tierheilkd. 2008 Nov;150(11):565-9. doi: 10.1024/0036-7281.150.11.565.
Primary (extranodal) malignant lymphoma limited exclusively to the urinary bladder is an extremely rare disorder in both humans and animals and has to be differentiated from malignant lymphoma cases where a systemic (multicentric) lymphoma has spread to the bladder. We report a case of a 3-year old female spayed mixed breed dog presenting with gross haematuria and dysuria and diagnosed with a primary B-cell high-grade lymphoma of the urinary bladder without involvement of any other site. After treatment with a combination of hypofractionated external beam radiation and cytotoxic chemotherapy, rapid and complete remission of the tumor occurred. At present the dog is alive and has been in remission for 52 months.
原发性（结外）恶性淋巴瘤仅限于膀胱，在人类和动物中都是极为罕见的疾病，必须与系统性（多中心）淋巴瘤扩散至膀胱的恶性淋巴瘤病例相鉴别。我们报告一例3岁绝育的杂种雌性犬，表现为肉眼血尿和排尿困难，诊断为原发性膀胱B细胞高级别淋巴瘤，未累及其他任何部位。经低分割外照射和细胞毒性化疗联合治疗后，肿瘤迅速完全缓解。目前，这只犬存活，已缓解52个月。
