Chiarelli Giusy, Beaulieu Monica, Cozzolino Mario, Singh Suneet, Kiaii Mercedeh, Taylor Paul, Levin Adeera, Brancaccio Diego, Gallieni Maurizio
Nephrology and Dialysis Unit, San Paolo Hospital, University of Milan, Italy.
Perit Dial Int. 2008 Nov-Dec;28(6):585-90.
Peritoneal dialysis (PD) is a well-established renal replacement therapy for end-stage renal disease patients. Nonetheless, on an annual basis, at least 10% of patients shift from PD to hemodialysis for a variety of reasons. Thus the issue of vascular access creation needs to be addressed for this small but significant group of patients. Despite the relatively consistent number of dropouts, the creation of an arteriovenous fistula prior to transfer remains suboptimal, and variable from center to center. Literature for this specific area is poor and dated. Guidelines seem to suggest vascular access creation in high-risk failure patients, but they have no detailed criteria to select patients that would likely fail PD and therefore take advantage of a backup access. There is a need to better understand and predict patients that require conversion to hemodialysis to develop a plan that focuses on wellness and maximum quality of life in the lifecycle of PD patients. This review addresses the issue of vascular access planning in adult PD patients, presents the available literature on the topic and the current guidelines and recommendations, and describes a research agenda to guide decision making in clinical practice.
腹膜透析(PD)是一种成熟的针对终末期肾病患者的肾脏替代治疗方法。尽管如此,每年仍有至少10%的患者因各种原因从腹膜透析转为血液透析。因此,对于这一小部分但意义重大的患者群体,血管通路建立的问题需要得到解决。尽管退出腹膜透析的患者数量相对稳定,但在转至血液透析之前建立动静脉内瘘的情况仍不尽人意,且各中心之间存在差异。该特定领域的文献较少且陈旧。指南似乎建议在高风险失败患者中建立血管通路,但对于如何选择可能腹膜透析失败从而需要备用通路的患者,却没有详细标准。有必要更好地了解和预测需要转为血液透析的患者,以制定一个关注腹膜透析患者生命周期内健康状况和最大生活质量的计划。本综述探讨了成年腹膜透析患者血管通路规划的问题,介绍了该主题的现有文献、当前指南和建议,并描述了一个指导临床实践决策的研究议程。