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腹透和血透的转换真的是一个渐进的过程吗?

Is transition between peritoneal dialysis and hemodialysis really a gradual process?

机构信息

Nephrology Department, CHU Clemenceau, Caen, France.

出版信息

Perit Dial Int. 2013 Jul-Aug;33(4):391-7. doi: 10.3747/pdi.2011.00134. Epub 2013 Jan 2.

Abstract

BACKGROUND

Transfer to hemodialysis (HD) is a frequent cause of peritoneal dialysis (PD) cessation. In the present study, we set out to describe the transition period between PD and HD.

METHODS

All patients in 4 centers of Basse-Normandie who had been treated with PD for more than 90 days and who were permanently transferred to HD between 1 January 2005 and 31 December 2009 were retrospectively reviewed. The rate of unplanned HD start was evaluated.

RESULTS

In the 60 patients (39 men, 21 women) included in the study, median score on the Charlson comorbidity index at PD initiation was 5 [interquartile range (IQR): 3 - 7], median age at HD initiation was 62 years (IQR: 54 - 76 years), and median duration on PD was 22 months (IQR: 12 - 36 months). Among the 60 patients, 37 had an unplanned HD initiation. Peritonitis was the most frequent cause of unplanned HD start (n = 20), and dialysis inadequacy (n = 11), the main cause of planned HD start. During the transition period, all patients were hospitalized. Median duration of hospitalization was 4.5 days (IQR: 0 - 25.5 days). Within 2 months after HD initiation, 9 patients died. Two months after starting HD, 6 of the remaining 51 patients were being treated in a self-care HD unit and only 23 patients had a mature fistula.

CONCLUSIONS

Unplanned HD start is a common problem in patients transferred from PD. Further studies are needed to improve the rate of planned HD start in PD patients transferred to HD.

摘要

背景

转至血液透析(HD)是腹膜透析(PD)停止的常见原因。在本研究中,我们旨在描述 PD 与 HD 之间的过渡时期。

方法

回顾性分析了 2005 年 1 月 1 日至 2009 年 12 月 31 日期间在诺曼底下区 4 个中心接受 PD 治疗超过 90 天并永久转至 HD 的所有患者。评估了非计划性 HD 开始的比率。

结果

在纳入研究的 60 例患者(39 名男性,21 名女性)中,PD 起始时 Charlson 合并症指数中位数为 5 [四分位距(IQR):3-7],HD 起始时年龄中位数为 62 岁(IQR:54-76 岁),PD 持续时间中位数为 22 个月(IQR:12-36 个月)。在 60 例患者中,37 例发生了非计划性 HD 起始。腹膜炎是非计划性 HD 起始的最常见原因(n=20),透析不充分(n=11)是计划性 HD 起始的主要原因。在过渡期间,所有患者均住院。中位住院时间为 4.5 天(IQR:0-25.5 天)。在开始 HD 后 2 个月内,有 9 例患者死亡。在开始 HD 后 2 个月,51 例患者中有 6 例在自我护理 HD 单位接受治疗,只有 23 例患者有成熟的瘘管。

结论

从 PD 转至 HD 的患者中,非计划性 HD 起始是一个常见问题。需要进一步研究以提高转至 HD 的 PD 患者计划性 HD 起始的比率。

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