Haag Juergen, Borst Alexander
Max-Planck-Institute of Neurobiology, Department of Systems and Computational Neurobiology, Martinsried Germany.
Front Neurosci. 2007 Oct 15;1(1):111-21. doi: 10.3389/neuro.01.1.1.008.2007. eCollection 2007 Nov.
Neurons in the visual system of the blowfly have large receptive fields that are selective for specific optic flow fields. Here, we studied the neural mechanisms underlying flow-field selectivity in proximal Vertical System (VS)-cells, a particular subset of tangential cells in the fly. These cells have local preferred directions that are distributed such as to match the flow field occurring during a rotation of the fly. However, the neural circuitry leading to this selectivity is not fully understood. Through dual intracellular recordings from proximal VS cells and other tangential cells, we characterized the specific wiring between VS cells themselves and between proximal VS cells and horizontal sensitive tangential cells. We discovered a spiking neuron (Vi) involved in this circuitry that has not been described before. This neuron turned out to be connected to proximal VS cells via gap junctions and, in addition, it was found to be inhibitory onto VS1.
果蝇视觉系统中的神经元具有大的感受野，这些感受野对特定的光流场具有选择性。在这里，我们研究了近端垂直系统（VS）细胞中流场选择性的神经机制，VS细胞是果蝇中一类特定的切向细胞子集。这些细胞具有局部偏好方向，其分布方式与果蝇旋转过程中出现的流场相匹配。然而，导致这种选择性的神经回路尚未完全了解。通过对近端VS细胞和其他切向细胞进行双细胞内记录，我们描绘了VS细胞自身之间以及近端VS细胞与水平敏感切向细胞之间的特定连接方式。我们发现了一个参与该回路的尖峰神经元（Vi），此前尚未有过描述。结果表明，这个神经元通过缝隙连接与近端VS细胞相连，此外，还发现它对VS1具有抑制作用。
Zotero 插件
