Termeer Maurice, Oliván Bescós Javier, Breeuwer Marcel, Vilanova Anna, Gerritsen Frans, Gröller M Eduard, Nagel Eike
Vienna University of Technology.
IEEE Trans Vis Comput Graph. 2008 Nov-Dec;14(6):1595-602. doi: 10.1109/TVCG.2008.180.
Visually assessing the effect of the coronary artery anatomy on the perfusion of the heart muscle in patients with coronary artery disease remains a challenging task. We explore the feasibility of visualizing this effect on perfusion using a numerical approach. We perform a computational simulation of the way blood is perfused throughout the myocardium purely based on information from a three-dimensional anatomical tomographic scan. The results are subsequently visualized using both three-dimensional visualizations and bull's eye plots, partially inspired by approaches currently common in medical practice. Our approach results in a comprehensive visualization of the coronary anatomy that compares well to visualizations commonly used for other scanning technologies. We demonstrate techniques giving detailed insight in blood supply, coronary territories and feeding coronary arteries of a selected region. We demonstrate the advantages of our approach through visualizations that show information which commonly cannot be directly observed in scanning data, such as a separate visualization of the supply from each coronary artery. We thus show that the results of a computational simulation can be effectively visualized and facilitate visually correlating these results to for example perfusion data.
在冠心病患者中,通过视觉评估冠状动脉解剖结构对心肌灌注的影响仍然是一项具有挑战性的任务。我们探索使用数值方法可视化这种对灌注的影响的可行性。我们纯粹基于三维解剖断层扫描的信息,对血液在整个心肌中的灌注方式进行了计算模拟。随后,使用三维可视化和靶心图对结果进行可视化,部分灵感来自当前医学实践中常用的方法。我们的方法能够全面可视化冠状动脉解剖结构,与其他扫描技术常用的可视化方法相比效果良好。我们展示了一些技术,这些技术能够深入了解选定区域的血液供应、冠状动脉区域和供血冠状动脉。我们通过可视化展示了我们方法的优势,这些可视化展示了通常在扫描数据中无法直接观察到的信息,例如每条冠状动脉供血的单独可视化。因此,我们表明计算模拟的结果可以有效地可视化,并有助于将这些结果与例如灌注数据进行视觉关联。