Maniwa Yoshimasa, Yoshimura Masahiro, Takata Masahiko, Nishimura Yoshihiro, Ohno Yoshiharu
Divisions of Thoracic Surgery, Kobe University Graduate School of Medicine, Kobe, Japan.
Ann Thorac Cardiovasc Surg. 2008 Oct;14(5):319-21.
Malignant pleural mesothelioma (MPM) is an aggressive and fatal tumor of the pleura and its incidence has been increasing as a result of the widespread use of asbestos worldwide. Numerous chemotherapeutic agents have been tested in many clinical trials, but the response rate does not exceed 20% for most of the investigated regimens. Here we report a case of MPM in which the chemotherapy based on the chemosensitivity test was very effective on palliation with stable disease for a long time.
恶性胸膜间皮瘤(MPM)是一种侵袭性且致命的胸膜肿瘤,由于石棉在全球范围内的广泛使用,其发病率一直在上升。许多化疗药物已在众多临床试验中进行了测试,但对于大多数所研究的治疗方案,缓解率不超过20%。在此,我们报告一例MPM病例,其中基于化疗敏感性测试的化疗在长期缓解疾病方面非常有效。