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基于恶性胸膜间皮瘤化疗敏感性测试的有效化疗。

Effective chemotherapy based on a chemosensitivity test for malignant pleural mesothelioma.

作者信息

Maniwa Yoshimasa, Yoshimura Masahiro, Takata Masahiko, Nishimura Yoshihiro, Ohno Yoshiharu

机构信息

Divisions of Thoracic Surgery, Kobe University Graduate School of Medicine, Kobe, Japan.

出版信息

Ann Thorac Cardiovasc Surg. 2008 Oct;14(5):319-21.

PMID:18989249
Abstract

Malignant pleural mesothelioma (MPM) is an aggressive and fatal tumor of the pleura and its incidence has been increasing as a result of the widespread use of asbestos worldwide. Numerous chemotherapeutic agents have been tested in many clinical trials, but the response rate does not exceed 20% for most of the investigated regimens. Here we report a case of MPM in which the chemotherapy based on the chemosensitivity test was very effective on palliation with stable disease for a long time.

摘要

恶性胸膜间皮瘤(MPM)是一种侵袭性且致命的胸膜肿瘤,由于石棉在全球范围内的广泛使用,其发病率一直在上升。许多化疗药物已在众多临床试验中进行了测试,但对于大多数所研究的治疗方案,缓解率不超过20%。在此,我们报告一例MPM病例,其中基于化疗敏感性测试的化疗在长期缓解疾病方面非常有效。

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