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[生育能力外科修复的当前进展]

[Current aspects of surgical restoration of fertility].

作者信息

Popken G, Schwarzer J U

机构信息

HELIOS-Kliniken Berlin Buch, Schwanebecker Chaussee 50, 13125 Berlin.

出版信息

Urologe A. 2008 Dec;47(12):1568-72. doi: 10.1007/s00120-008-1803-5.

Abstract

Obstruction of the seminal ducts is the cause of infertility in about 5% of patients. It can be congenital or arise as the result of secondary changes. The reconstruction of the duct undertaken depends on the site of the obstruction. The introduction of microsurgical techniques has revolutionized the treatment of male infertility.A tubulovasostomy is carried out if the obstruction lies in the region of the epididymis. Such an anastomosis requires, owing to the minute anatomical relationships involved, a microsurgical procedure. For an obstruction of the vas deferens a vasovasostomy is required. Many investigations have shown that microsurgical techniques are also necessary for this procedure if a satisfactory success rate is to be achieved. The double-layer technique is the standard method for vasovasostomy. Transurethral resection of the ejaculatory ducts (TURED) is required for the very rare obstruction in this region, and men with an obstruction here cannot be regarded as forming a homogeneous group.Before advising an infertile couple it is necessary to investigate the individual conditions and possibilities. Because of the high success rate obtainable today by surgical reconstruction of the seminal ducts, this must constitute the first type of treatment to be considered, before any of the procedures of reproductive medicine are undertaken.

摘要

在约5%的患者中,输精管道梗阻是导致不育的原因。它可以是先天性的,也可由继发性改变引起。进行的管道重建取决于梗阻部位。显微外科技术的引入彻底改变了男性不育症的治疗方法。如果梗阻位于附睾区域,则进行附睾输精管吻合术。由于涉及微小的解剖关系,这种吻合需要采用显微外科手术。对于输精管梗阻,需要进行输精管吻合术。许多研究表明,如果要获得满意的成功率,该手术也需要显微外科技术。双层技术是输精管吻合术的标准方法。对于该区域非常罕见的梗阻,需要行经尿道射精管切除术(TURED),在此处有梗阻的男性不能被视为一个同质群体。在为不育夫妇提供建议之前,有必要调查个体情况和可能性。由于如今通过输精管道的外科重建可获得较高的成功率,在采取任何生殖医学程序之前,这必须作为首先要考虑的治疗方式。

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