Salameh Fares, Perla David, Solomon Michal, Gamus Dorit, Barzilai Aviv, Greenberger Shoshana, Trau Henri
Department of Dermatology, The Chaim Sheba Medical Center, Tel Hashomer, The Sackler School of Medicine, Tel Aviv University, Israel.
J Altern Complement Med. 2008 Oct;14(8):1043-8. doi: 10.1089/acm.2008.0162.
Patients with atopic dermatitis increasingly use complementary medicine.
The objective of this study was to assess the effectiveness of the combination of Chinese herbal medicine and acupuncture for the treatment of atopic dermatitis.
Twenty (20) patients between the ages of 13 and 48 who had mild-to-severe atopic dermatitis were given a combined treatment of acupuncture and Chinese herbal medicine and were followed prospectively. The patients received acupuncture treatment twice a week and the Chinese herbal formula 3 times daily for a total of 12 weeks. Assessments were performed before treatment, and at weeks 3, 6, 9, and 12 of treatment. The primary outcomes were defined as the changes in the Eczema Area and Severity Index (EASI), Dermatology Life Quality Index (DLQI), and patient assessment of itch measured on a visual analogue scale (VAS).
After 12 weeks of treatment, an improvement in EASI was noted in 100% of patients, when compared with the baseline. The mean EASI fell from 4.99 to 1.81; the median percentage of decrease was 63.5%. Moreover, 78.8% of patients experienced a reduction in DLQI and VAS, as compared with the baseline. The mean DLQI decreased from 12.5 to 7.6 at the end of treatment, with 39.1% improvement. Mean VAS decreased from 6.8 to 3.7, with 44.7% improvement. No adverse effects were observed.
The results of this study suggest that the combination of acupuncture and Chinese herbal medicine have a beneficial effect on patients with atopic dermatitis and may offer better results than Chinese herbal medicine alone.
特应性皮炎患者越来越多地使用补充替代医学。
本研究旨在评估中药与针灸联合治疗特应性皮炎的有效性。
选取20例年龄在13至48岁之间、患有轻至重度特应性皮炎的患者,给予针灸和中药联合治疗,并进行前瞻性随访。患者每周接受两次针灸治疗,中药方剂每日服用3次,共治疗12周。在治疗前以及治疗第3、6、9和12周进行评估。主要结局指标定义为湿疹面积和严重程度指数(EASI)、皮肤病生活质量指数(DLQI)的变化,以及患者使用视觉模拟量表(VAS)对瘙痒程度的评估。
治疗12周后,与基线相比,所有患者的EASI均有改善。EASI均值从4.99降至1.81;下降中位数百分比为63.5%。此外,与基线相比,78.8%的患者DLQI和VAS有所降低。治疗结束时,DLQI均值从12.5降至7.6,改善率为39.1%。VAS均值从6.8降至3.7,改善率为44.7%。未观察到不良反应。
本研究结果表明,针灸与中药联合治疗对特应性皮炎患者有有益作用,且可能比单纯使用中药效果更好。