Tello Ana María, Lebrón-Aguilar Rosa, Quintanilla-López Jesús Eduardo, Santiuste José María
Department of Structure and Molecular Dynamics, Institute of Physical Chemistry Rocasolano, Serrano 119, 28006 Madrid, Spain.
J Chromatogr A. 2009 Mar 6;1216(10):1630-9. doi: 10.1016/j.chroma.2008.10.025. Epub 2008 Oct 14.
Experimental isothermal retention indices (I) at 348, 363, 378 and 393 K of 52 solutes of varied polarity on seven different poly(cyanopropylmethylsiloxane) stationary phases with cyanopropyl group percentages between 0% and 75% have been determined by a well-proven, accurate method. Some of these I values were obtained on new stationary phases with cyanopropyl percentages never used before. The influence of column temperature and polymer polarity on I was thoroughly investigated. Finally, retention models were developed relating I values to physicochemical and molecular properties by multiple linear regression. The best model of retention index prediction for the proposed cyanosilicones involves the Abraham's descriptors.
采用一种经过充分验证的精确方法，测定了52种不同极性溶质在7种不同的氰丙基含量介于0%至75%之间的聚（氰丙基甲基硅氧烷）固定相上，于348 K、363 K、378 K和393 K时的实验等温保留指数（I）。其中一些I值是在以前从未使用过的氰丙基含量的新型固定相上获得的。深入研究了柱温和聚合物极性对I的影响。最后，通过多元线性回归建立了将I值与物理化学和分子性质相关联的保留模型。对于所提出的氰基硅氧烷，最佳的保留指数预测模型涉及亚伯拉罕描述符。
