大肠杆菌中CitAB对柠檬酸发酵的厌氧调控
Anaerobic regulation of citrate fermentation by CitAB in Escherichia coli.
作者信息
Yamamoto Kaneyoshi, Matsumoto Fumika, Oshima Taku, Fujita Nobuyuki, Ogasawara Naotake, Ishihama Akira
机构信息
Department of Advanced Bioscience, Kinki University, Nara, Japan.
出版信息
Biosci Biotechnol Biochem. 2008 Nov;72(11):3011-4. doi: 10.1271/bbb.80301. Epub 2008 Nov 7.
In Escherichia coli, CitB, a cognate response regulator of CitA, specifically bound to the promoter regions for mdh, citA, citC, and exuT. Transcription of these genes was induced by citrate under anaerobic conditions in a CitAB-dependent manner. Taking this together, we conclude that CitAB is the master regulatory system that activates the set of genes involved in citrate fermentation in E. coli.
在大肠杆菌中，CitB作为CitA的同源应答调节因子，特异性结合到mdh、citA、citC和exuT的启动子区域。在厌氧条件下，这些基因的转录由柠檬酸盐以CitAB依赖的方式诱导。综合这些结果，我们得出结论，CitAB是激活大肠杆菌中参与柠檬酸盐发酵的一组基因的主要调控系统。
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