Hofsteenge G H, Weijs P J M, Chin A Paw M J M, Delemarre-van de Waal H A
VU Medisch Centrum, dienst Diëtetiek en Voedingswetenschappen, Postbus 7057, 1007 MB Amsterdam.
Ned Tijdschr Geneeskd. 2008 Jul 19;152(29):1628-33.
To evaluate the effect of Go4it, a multidisciplinary group education programme for adolescents with overweight or obesity.
Uncontrolled intervention study.
At the obesity outpatient clinic of the Transmural Research and Treatment Centre for Overweight and Obese Children of the VU University Medical Center, Amsterdam, The Netherlands, a group education programme was developed for adolescents (age 12-18 year) who are overweight or obese. Obese adolescents who were referred to the obesity outpatient clinic were asked to participate. During 7 sessions (one session every two weeks) the adolescents were educated on the health consequences of obesity, diet, physical activity, energy balance, improving self-esteem and how to handle bullying and other difficult situations. All sessions were held in groups of 8-10 adolescents. In addition, two sessions were organised for the parents concerning the health consequences of obesity, diet, and physical activity. Body weight and height, glucose tolerance (by an oral glucose tolerance test; OGTT), and insulin resistance were measured at enrolment into the Go4it programme and 6 months later.
In total, 93 adolescents (39 boys, 54 girls) were included with a mean age of 3.9 (SD: 1.7) years. Of those, 69 adolescents (74%) attended at least 6 out of 7 sessions of the education programme. Stabilisation or reduction in obesity levels following completion of Go4it was achieved in 51 (74%) of these participants. 50 adolescents had a second OGTT. The BMI standard deviation score (BMI-sds) decreased by 4.3% for boys (p = 0.020) and 3.3% for girls (p = 0.017). Among girls, fasting blood glucose levels decreased by an average of 0.37 mmol/l (95% CI: 0.14-0.60) and insulin concentrations decreased by an average of 299 pmol/l (95% CI: 71-528).
Participation in the Go4it education programme is accompanied by a stabilisation or reduction in the level of obesity and has favourable effects on glucose and insulin metabolism.
评估Go4it（一项针对超重或肥胖青少年的多学科团体教育项目）的效果。
非对照干预研究。
在荷兰阿姆斯特丹VU大学医学中心超重与肥胖儿童跨学科研究与治疗中心的肥胖门诊，为超重或肥胖的青少年（12至18岁）制定了一项团体教育项目。被转诊至肥胖门诊的肥胖青少年被邀请参加。在7次课程（每两周一次）中，青少年接受了关于肥胖的健康后果、饮食、体育活动、能量平衡、提高自尊以及如何应对欺凌和其他困难情况的教育。所有课程均以8至10名青少年为一组进行。此外，还为家长组织了两次关于肥胖的健康后果、饮食和体育活动的课程。在参加Go4it项目时以及6个月后测量体重和身高、葡萄糖耐量（通过口服葡萄糖耐量试验；OGTT）和胰岛素抵抗。
总共纳入了93名青少年（39名男孩，54名女孩），平均年龄为13.9（标准差：1.7）岁。其中，69名青少年（74%）参加了该教育项目7次课程中的至少6次。在这些参与者中，51名（74%）在完成Go4it项目后肥胖水平得到稳定或降低。50名青少年进行了第二次OGTT。男孩的BMI标准差评分（BMI-sds）下降了4.3%（p = 0.020），女孩下降了3.3%（p = 0.017）。在女孩中，空腹血糖水平平均下降了0.37 mmol/l（95%置信区间：0.14 - 0.60），胰岛素浓度平均下降了299 pmol/l（95%置信区间：71 - 528）。
参与Go4it教育项目伴随着肥胖水平的稳定或降低，并对葡萄糖和胰岛素代谢产生有利影响。
