Hofsteenge Geesje H, Chinapaw Marijke J M, Weijs Peter J M, van Tulder Maurits W, Delemarre-van de Waal Henriette A
Dept, of Nutrition & Dietetics, VU University Medical Center, Amsterdam, The Netherlands.
BMC Public Health. 2008 Dec 16;8:410. doi: 10.1186/1471-2458-8-410.
In the Netherlands, the first adolescents with diabetes mellitus type 2 as a result of obesity have recently been diagnosed. Therefore, it is very important that programs aiming at the prevention of type 2 diabetes of obese adolescents are developed and evaluated.
Go4it is a multidisciplinary group treatment that focuses on: 1) increasing awareness of the current dietary and physical activity behaviour (i.e. energy balance behaviour), 2) improving diet, 3) decreasing sedentary behaviour, 4) increasing levels of physical activity, and 5) coping with difficult situations. Go4it consists of 7 sessions with an interval of 2-3 weeks.The effectiveness of the multidisciplinary group treatment compared with usual care (i.e. referral to a dietician) was evaluated in a randomised controlled trial. We examined effects on BMI(sds), body composition, energy expenditure, glucose tolerance and insulin resistance (primary outcome measure), as well as dietary and physical activity behaviour and quality of life. An economic evaluation from a societal perspective was conducted alongside the randomised trial to evaluate the cost-effectiveness of the multidisciplinary treatment program vs. usual care.
In this paper we described a multidisciplinary treatment program (Go4it) for obese adolescents and the design of a randomised controlled trial and economic evaluation to evaluate its effectiveness and cost-effectiveness.
Netherlands Trial Register (ISRCTN27626398).
在荷兰，最近已诊断出首批因肥胖导致2型糖尿病的青少年。因此，制定并评估旨在预防肥胖青少年患2型糖尿病的项目非常重要。
Go4it是一种多学科小组治疗方法，重点关注：1）提高对当前饮食和身体活动行为（即能量平衡行为）的认识，2）改善饮食，3）减少久坐行为，4）增加身体活动水平，5）应对困难情况。Go4it包括7次治疗课程，间隔为2至3周。在一项随机对照试验中评估了这种多学科小组治疗方法与常规护理（即转介给营养师）相比的有效性。我们研究了对BMI（标准差评分）、身体成分、能量消耗、葡萄糖耐量和胰岛素抵抗（主要结局指标）的影响，以及饮食和身体活动行为及生活质量。在随机试验的同时，从社会角度进行了经济评估，以评估多学科治疗方案与常规护理相比的成本效益。
在本文中，我们描述了一种针对肥胖青少年的多学科治疗方案（Go4it）以及一项随机对照试验和经济评估的设计，以评估其有效性和成本效益。
荷兰试验注册库（ISRCTN27626398）。
