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[自然生理条件下大脑中核糖体RNA含量及核糖核酸酶活性的变化]

[Changes in the content of ribosomal RNA and the activity of ribosomal RNAase in the brain under natural physiological conditions].

作者信息

Khachatryan G S, Alaverdyan A A

出版信息

Vopr Med Khim. 1975 May-Jun;21(3):264-8.

PMID:1900
Abstract

Optimal activity of RNAase from brain ribosomal fraction was observed at pH 5.4 and pH 7.9. After alimentary and conditioned-alimentary stimulation content of rRNA was significantly increased in brain, but the RNAase activity was decreased more than two-fold. After conditioned-alimentary inhibition content of rRNA was slightly decreased as compared to experiments with alimentary and conditioned-alimentary stimulation, but it was distinctly higher than in control. As compared with alimentary stimulation in the conditioned-alimentary stimulation the RNAase activity was increased at pH 5.4 and decreased at pH 7.9.

摘要

在pH 5.4和pH 7.9时观察到脑核糖体部分的核糖核酸酶活性最佳。经食物性和条件性食物刺激后,脑中rRNA的含量显著增加,但核糖核酸酶活性下降了两倍多。与食物性和条件性食物刺激实验相比,经条件性食物抑制后,rRNA的含量略有下降,但明显高于对照组。与食物性刺激相比,在条件性食物刺激中,pH 5.4时核糖核酸酶活性增加,pH 7.9时活性降低。

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