Balderrábano-Saucedo Norma A, Vizcaíno-Alarcón Alfredo, Reyes-de la Cruz Lorenzo, Espinosa-Islas Gonzalo, Arévalo-Salas Alexis, Segura-Stanford Begoña
Departamento de Cardiología, Hospital Infantil de México Federico Gómez, México DF, Mexico.
Rev Esp Cardiol. 2008 Nov;61(11):1126-33.
Lifetime prognosis following successful repair of aortic coarctation can be affected by a number of late complications. The objective of this study was to assess left ventricular function in these patients and to identify factors that predispose to functional abnormalities.
The study involved patients who had undergone repair of aortic coarctation and who had a pressure gradient pound 15 mmHg after repair and normal systemic blood pressure. Echocardiographic data collected before repair and the results of the most recent postoperative left ventricular function studies were analyzed.
The study involved 40 patients and 31 controls. Their mean age at repair was 6.9 years and the mean follow-up period was 4.25 years. During follow-up, the ejection fraction and the shortening fraction were observed to increase in 82.5% and 67.5% of patients, respectively. The myocardial performance index was abnormal in 47.5% of patients. The highest myocardial performance indices were observed in patients with arterial hypertension at diagnosis, in those who were aged over 4 years when they underwent repair, and in those with the most abnormal left ventricles before repair.
Measurement of the myocardial performance index showed that global left ventricular function was abnormal in 47.5% of patients after successful repair of aortic coarctation despite functional parameters being normal or elevated.
主动脉缩窄成功修复后的终生预后可能受到多种晚期并发症的影响。本研究的目的是评估这些患者的左心室功能,并确定易导致功能异常的因素。
本研究纳入了接受主动脉缩窄修复且修复后压力阶差≥15 mmHg且全身血压正常的患者。分析了修复前收集的超声心动图数据以及最近一次术后左心室功能研究的结果。
本研究纳入了40例患者和31例对照。他们修复时的平均年龄为6.9岁,平均随访期为4.25年。随访期间,分别观察到82.5%和67.5%的患者射血分数和缩短分数增加。47.5%的患者心肌性能指数异常。诊断时患有动脉高血压的患者、修复时年龄超过4岁的患者以及修复前左心室最异常的患者的心肌性能指数最高。
心肌性能指数测量显示,尽管功能参数正常或升高,但47.5%的主动脉缩窄成功修复患者的整体左心室功能仍异常。