Takano Masamichi, Yamamoto Masanori, Inami Shigenobu, Xie Yong, Murakami Daisuke, Okamatsu Kentaro, Ohba Takayoshi, Seino Yoshihiko, Mizuno Kyoichi
Division of Cardiology, Nippon Medical School, Tokyo, Japan.
Circ J. 2009 Jan;73(1):190-3. doi: 10.1253/circj.cj-07-0924. Epub 2008 Nov 11.
A polytetrafluoroethylene (PTFE)-covered stent is specially used to treat coronary perforation complicating percutaneous intervention in order to prevent the aneurysm from rupturing, but until now it has not been known if endothelialization occurs inside this type of stent. A patient with a giant aneurysm of the right coronary artery underwent successful implantation of a PTFE-covered stent. Angiography at 9-month follow-up showed focal restenosis at the proximal edge of the stent and coronary angioscopy revealed restenosis as a result of thrombus formation. Absence of endothelialization in the covered stent was also detected by angioscopy and optical coherence tomography. These findings suggest that in-stent thrombosis must be prevented after PTFE-covered stent implantation.
聚四氟乙烯(PTFE)覆膜支架专门用于治疗经皮介入治疗时并发的冠状动脉穿孔,以防止动脉瘤破裂,但迄今为止,尚不清楚这种类型的支架内部是否会发生内皮化。一名右冠状动脉巨大动脉瘤患者成功植入了PTFE覆膜支架。9个月随访时的血管造影显示支架近端边缘有局灶性再狭窄,冠状动脉血管镜检查显示再狭窄是由血栓形成所致。血管镜检查和光学相干断层扫描也检测到覆膜支架内无内皮化。这些发现提示,PTFE覆膜支架植入后必须预防支架内血栓形成。