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慢性心包缩窄诱发严重缺血性肝炎,表现为低血糖发作。

Chronic pericardial constriction induced severe ischemic hepatitis manifesting as hypoglycemic attack.

作者信息

Nomura Tetsuya, Keira Natsuya, Urakabe Yota, Naito Daisuke, Nakayama Mayuka, Kido Atsumichi, Kanemasa Hidetoshi, Matsubara Hiroaki, Tatsumi Tetsuya

机构信息

Department of Cardiovascular Medicine, Nantan General Hospital, Nantan, Japan.

出版信息

Circ J. 2009 Jan;73(1):183-6. doi: 10.1253/circj.cj-07-0881. Epub 2008 Nov 11.

Abstract

Ischemic hepatitis, otherwise known as "shock liver", is characterized by a massive, but transient increase in serum transaminase levels, usually associated with cardiac failure. A patient who did not have a predisposition to hypoglycemia was discovered at home with disturbed consciousness caused by hypoglycemia. She had been diagnosed as having constrictive pericarditis several years earlier and had developed ischemic hepatitis. Though the high serum transaminase levels were rapidly normalized, severe jaundice gradually developed and the patient finally died of multiple organ failure. Hypoglycemia, which is considered secondary to reduced gluconeogenesis in the exhausted liver, is a rare complication of constrictive pericarditis.

摘要

缺血性肝炎,又称“休克肝”,其特征是血清转氨酶水平大幅但短暂升高,通常与心力衰竭有关。一名无低血糖易患倾向的患者在家中因低血糖导致意识障碍被发现。她几年前被诊断患有缩窄性心包炎,并已发展为缺血性肝炎。尽管血清转氨酶水平迅速恢复正常,但严重黄疸逐渐出现,患者最终死于多器官功能衰竭。低血糖被认为是由于衰竭肝脏中糖异生减少所致,是缩窄性心包炎的一种罕见并发症。

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