A型肉毒杆菌毒素治疗多发性皮肤平滑肌瘤患者
Botulinum toxin type A--treatment of a patient with multiple cutaneous piloleiomyomas.
作者信息
Sifaki Maria K, Krueger-Krasagakis Sabine, Koutsopoulos Anastasios, Evangelou Georgios I, Tosca Androniki D
机构信息
Department of Dermatology, Faculty of Medicine, University of Crete, Heraklion, Greece.
出版信息
Dermatology. 2009;218(1):44-7. doi: 10.1159/000173695. Epub 2008 Nov 12.
BACKGROUND
Treatment of multiple cutaneous piloleiomyomas which are rare, frequently painful, benign tumors originating from the arrector pilorum muscle of hair follicles is difficult.
OBJECTIVE
To determine the efficiency of botulinum toxin type A (BT-A) treatment for pain relief of cutaneous piloleiomyomas.
METHODS
A patient with multiple painful piloleiomyomas was treated with local injections of 200 units of BT-A.
RESULTS
There was a rapid and sustained decrease in pain. Treatment was repeated every 3 months for 2 years with the same efficacy.
CONCLUSION
BT-A may be a promising new treatment option for multiple painful cutaneous piloleiomyomas.
背景
多发性皮肤平滑肌瘤是一种罕见的、常伴有疼痛的良性肿瘤，起源于毛囊的立毛肌，其治疗较为困难。
目的
确定A型肉毒杆菌毒素（BT-A）治疗皮肤平滑肌瘤疼痛缓解的疗效。
方法
对一名患有多发性疼痛性皮肤平滑肌瘤的患者进行局部注射200单位BT-A治疗。
结果
疼痛迅速且持续减轻。每3个月重复治疗，持续2年，疗效相同。
结论
BT-A可能是治疗多发性疼痛性皮肤平滑肌瘤的一种有前景的新治疗选择。
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