Darby Jonathan, Buising Kirsty
Infectious Diseases Unit, St Vincent's Hospital, Fitzroy, Victoria.
Aust Fam Physician. 2008 Oct;37(10):812-5.
Community acquired pneumonia is a common condition presenting to general practitioners and emergency departments across Australia. Legionella is one of many pathogens responsible for community acquired pneumonia. Cases of Legionella may occur sporadically or as part of an outbreak.
This article describes the clinical manifestations of Legionella infection and provides clinicians with an approach to its diagnosis and management.
Legionella infection is typically associated with community acquired pneumonia, which can be severe. Features pointing to Legionella as a cause of pneumonia include the presence of gastrointestinal symptoms, especially diarrhoea; neurological symptoms, especially confusion; fever up to 40 degrees C; hyponatraemia; and hepatic dysfunction. However, none of these is required to make the diagnosis. Sometimes nonrespiratory symptoms can predominate. Diagnosis requires the use of special tests specific for Legionella, the most clinically useful being urinary antigen tests and serology. Recommended treatments include macrolide therapy or doxycycline.
社区获得性肺炎是澳大利亚全科医生和急诊科常见的病症。军团菌是导致社区获得性肺炎的众多病原体之一。军团菌病例可能散发性出现,也可能是暴发的一部分。
本文描述了军团菌感染的临床表现,并为临床医生提供其诊断和管理方法。
军团菌感染通常与社区获得性肺炎相关,后者可能较为严重。提示军团菌为肺炎病因的特征包括存在胃肠道症状,尤其是腹泻;神经症状,尤其是意识模糊;高达40摄氏度的发热;低钠血症;以及肝功能障碍。然而,诊断并不需要具备所有这些特征。有时非呼吸道症状可能占主导。诊断需要使用针对军团菌的特殊检测,临床上最有用的是尿抗原检测和血清学检测。推荐的治疗方法包括大环内酯类治疗或强力霉素治疗。