Whitcomb Emily L, Lukacz Emily S, Lawrence Jean M, Nager Charles W, Luber Karl M
Division of Urogynecology and Reconstructive Pelvic Surgery, Department of Reproductive Medicine, University of California, San Diego, CA, USA.
Int Urogynecol J Pelvic Floor Dysfunct. 2009 Mar;20(3):289-94. doi: 10.1007/s00192-008-0765-x. Epub 2008 Nov 11.
We aimed to determine the prevalence and bother from pelvic floor disorders (PFD) by obesity severity, hypothesizing that both would increase with higher degrees of obesity. We performed a secondary analysis of 1,155 females enrolled in an epidemiologic study that used a validated questionnaire to identify PFD. Prevalence and degree of bother were compared across three obesity groups. Logistic regression assessed the contribution of degree of obesity to the odds of having PFD. Prevalence of any PFD was highest in morbidly (57%) and severely (53%) obese compared to obese women (44%). Regression models demonstrated higher prevalence of pelvic organ prolapse, overactive bladder, stress urinary incontinence, and any PFD in morbidly compared to obese women and higher prevalence of stress urinary incontinence in severely obese compared to obese women. Degree of bother did not vary by degree of obesity. Prevalence of PFD increases with higher degrees of obesity.
我们旨在按肥胖严重程度确定盆底功能障碍（PFD）的患病率及困扰程度，假设两者均会随着肥胖程度的增加而上升。我们对参与一项流行病学研究的1155名女性进行了二次分析，该研究使用经过验证的问卷来识别PFD。我们比较了三个肥胖组的患病率及困扰程度。逻辑回归评估了肥胖程度对发生PFD几率的影响。与肥胖女性（44%）相比，病态肥胖（57%）和重度肥胖（53%）女性中任何一种PFD的患病率最高。回归模型显示，与肥胖女性相比，病态肥胖女性盆腔器官脱垂、膀胱过度活动症、压力性尿失禁及任何一种PFD的患病率更高；与肥胖女性相比，重度肥胖女性压力性尿失禁的患病率更高。困扰程度并未因肥胖程度而异。PFD的患病率随着肥胖程度的增加而上升。
