Nehgme Rodrigo A, Huddleston Amber R, Cheatham John P
Orlando Campus, Florida State University, Tallahassee, FL, USA.
Pediatr Cardiol. 2009 Apr;30(3):367-70. doi: 10.1007/s00246-008-9322-0. Epub 2008 Nov 11.
Atrial septal defect (ASD) closure by interventional catheterization techniques has been widely accepted and is considered a standard treatment for this congenital heart defect. We report the case of a 6-year-old girl who presented with progression of first-degree atrio-ventricular (AV) block to symptomatic, complete heart block after ASD closure with an Amplatzer septal occluder (ASO). Although she received steroids immediately after the procedure when second-degree AV block was seen, her AV conduction slowly deteriorated over 4 years, requiring permanent pacemaker implantation. We can only speculate that the injury to the conduction system was the result of persistent trauma, ischemia, or progressive scarring caused by the ASO on the AV nodal region. It is uncertain if early device removal would have prevented this complication. This case highlights the importance of cardiac rhythm monitoring following ASO implantation for ASD closure on long-term follow-up.
经介入导管技术闭合房间隔缺损(ASD)已被广泛接受,并被视为这种先天性心脏缺陷的标准治疗方法。我们报告了一名6岁女孩的病例,她在使用Amplatzer房间隔封堵器(ASO)闭合ASD后,一度房室(AV)传导阻滞进展为有症状的完全性心脏传导阻滞。尽管在术中发现二度AV传导阻滞时她立即接受了类固醇治疗,但她的AV传导在4年中逐渐恶化,需要植入永久性起搏器。我们只能推测,传导系统的损伤是由ASO对房室结区域造成的持续性创伤、缺血或渐进性瘢痕形成所致。早期取出装置是否能预防这种并发症尚不确定。该病例强调了在ASO植入闭合ASD后进行长期随访时心律监测的重要性。