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经胸微创术中使用器械闭合房间隔缺损后出现房室传导阻滞:一种罕见且严重的并发症。

Atrioventricular block subsequent to intraoperative device closure atrial septal defect with transthoracic minimal invasion; a rare and serious complication.

机构信息

Department of Cardiovascular Surgery, Union Hospital, Fujian Medical University, Fuzhou, P. R. China.

出版信息

PLoS One. 2012;7(12):e52726. doi: 10.1371/journal.pone.0052726. Epub 2012 Dec 28.

Abstract

OBJECTIVES

Atrioventricular block (AVB) is a infrequent and serious complication after percutaneous ASD closure. In this study, we report on the incidence of AVB associated with intraoperative device closure of the ASD with transthoracic minimal invasion, and the outcomes of this complication in our center.

METHODS

Between May 2006 and January 2011, a total of 213 secundum-type ASD patients were accepted in our hospital for intraoperative and transthoracic device closure with a domestic occluder. All patients were assessed by real-time transthoracic echocardiography (TTE) and electrocardiograph (ECG).

RESULTS

All patients were occluded successfully under this approach. Immediate postprocedure third-degree AVB was observed in two patients. Since heart rates were in the range of about 50 to 55 beats per minute, no intervention was needed except for close observation for one patient. Another patient who recovered sinus rhythm intermittently during the operation was fitted with a temporary pacemaker. Approximately one week following glucocorticoid treatment, the AVB resolved spontaneously in these two patients. Mobitz type II AVB occurred in three patients during the procedure. Two patients developed post-operative cardiac arrest and were rescued successfully with cardiopulmonary resuscitation. One other patient changed to Mobitz type I AVB after three days. During the follow-up period, which ranged from six months to five years, no further occurrence of AVB was found.

CONCLUSIONS

Intraoperative and transthoracic device closure of secundum ASDs with domestic occluder resulted in excellent closure rate. AVB is an infrequent but serious complication during and after device closure of a secundum ASD. AVB is a complication that warrants greater attention and long-term follow-up.

摘要

目的

房室传导阻滞(AVB)是经皮 ASD 关闭后罕见且严重的并发症。本研究报告了经胸微创术中使用经胸器械闭合 ASD 时与 AVB 相关的发生率,以及我们中心对该并发症的处理结果。

方法

2006 年 5 月至 2011 年 1 月,共有 213 例继发孔型 ASD 患者在我院接受经胸器械闭合术和国产封堵器。所有患者均接受实时经胸超声心动图(TTE)和心电图(ECG)评估。

结果

所有患者均成功接受了这种方法的治疗。术后即刻发现 2 例患者出现三度 AVB。由于心率在每分钟 50 至 55 次之间,除密切观察 1 例患者外,无需进行其他干预。另一名在手术过程中间歇性恢复窦性心律的患者则安装了临时起搏器。大约在糖皮质激素治疗后一周,这 2 例患者的 AVB 自行缓解。手术过程中,有 3 例患者出现莫氏 II 型 AVB。2 例患者发生术后心脏骤停,经心肺复苏成功抢救。另有 1 例患者在 3 天后转为莫氏 I 型 AVB。在 6 个月至 5 年的随访期间,未再发现其他 AVB 病例。

结论

经胸微创术中使用国产封堵器治疗继发孔型 ASD 的闭合率高。AVB 是经皮 ASD 封堵术中及术后少见但严重的并发症。AVB 是一种需要引起更多关注和长期随访的并发症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7097/3532427/f0d10e8580da/pone.0052726.g001.jpg

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