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Synthesis, antibacterial and antifungal activities of 3-(1,2,4-triazol-3-yl)-4-thiazolidinones.

作者信息

Ozkirimli Sumru, Kazan Fusun, Tunali Yağmur

机构信息

Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Istanbul University, Istanbul, Turkey.

出版信息

J Enzyme Inhib Med Chem. 2009 Apr;24(2):447-52. doi: 10.1080/14756360802188511.

Abstract

A new series of 3-(1,2,4-triazol-3-yl)-4-thiazolidinone derivatives has been synthesized by the reaction of Schiff bases of 3-amino-1,2,4-triazoles with mercaptoacetic acid and 2-mercaptopropionic acid. Their antibacterial and antifungal activities were evaluated against S. aureus, S. epidermidis, C. albicans and C. glabrata.

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