Suppr超能文献

成功进行搭桥手术后,外周动脉疾病(PAD)患者健康相关生活质量的改善。

Improvement of the quality of life concerning the health of patients with peripheral arterial disease (PAD) after successful bypass surgery.

作者信息

Wohlgemuth W A, Safonova O, Engelhardt M, Freitag M, Wölfle K, Kirchhof K

机构信息

Klinikum Augsburg, Klinik für Diagnostische Radiologie und Neuroradiologie, Augsburg, Germany.

出版信息

Vasa. 2008 Nov;37(4):338-44. doi: 10.1024/0301-1526.37.4.338.

Abstract

BACKGROUND

To test whether quality of life depends on the psyche of patients after successful bypass surgery for peripheral arterial disease (PAD).

PATIENTS AND METHODS

A total of 74 consecutive patients aged 36-69 years (57.7 +/- 8.8 years) with symptomatic PAD in the stages Fontaine IIb-IV were enrolled in a prospective study after successful bypass surgery. Because of bypass failure and one death during the study period, 11 of these patients were excluded from evaluation. Prior to surgery, Doppler sonography and digital subtraction angiography were carried out in all patients. Before and after revascularization, the ankle / brachial index (ABI) was determined in all study objects and the pain free walking distance (PFWD) in those with PAD stage Fontaine IIb. Health-related quality of life was measured by using the "Medical Outcomes Study Group Short Form 36" (SF-36), and personality was determined by employing the Psycho-Diagnostic-Test (PDT).

RESULTS

After surgery, there was an increase in ABI from 0.32 +/- 0.13 to 0.79 +/- 0.19 (p < .01), in PFWD from 42.6 m +/- 38.6 m to 419.7 m +/- 152.3 m (p < .01), and in the SF-36 scales "Physical functioning", "Bodily pain", "General health perceptions", and "Role-functioning physical" (p < .05). ABI correlated positively with "Bodily pain" (p < .01), "General health perceptions" (p < .01) and "Mental health" (p < .05). Among SF-36 and PDT-scales, "Role-functioning physical" correlated negatively with "Moodiness" / "Neuroticism" (p < .05), and "Social functioning" correlated positively with "General activity" (p < .01).

CONCLUSIONS

Whether objective clinical improvement increases quality of life mainly depends on the psyche of patients: A high level of general activity favors an improved quality of life and neurotic characteristics are more likely to be a hindrance.

摘要

背景

为了测试在成功进行外周动脉疾病(PAD)搭桥手术后,生活质量是否取决于患者的心理状态。

患者与方法

共有74例年龄在36 - 69岁(平均57.7±8.8岁)、处于Fontaine IIb - IV期有症状的PAD患者在成功进行搭桥手术后被纳入一项前瞻性研究。由于在研究期间出现搭桥失败和1例死亡,其中11例患者被排除在评估之外。所有患者在手术前均进行了多普勒超声检查和数字减影血管造影。在血运重建前后,对所有研究对象测定踝/臂指数(ABI),对处于Fontaine IIb期的PAD患者测定无痛步行距离(PFWD)。使用“医学结局研究组简表36”(SF - 36)测量健康相关生活质量,并采用心理诊断测试(PDT)确定人格特征。

结果

手术后,ABI从0.32±0.13增加到0.79±0.19(p < 0.01),PFWD从42.6 m±38.6 m增加到419.7 m±152.3 m(p < 0.01),SF - 36量表中的“身体功能”“身体疼痛”“总体健康感知”和“身体角色功能”也有所改善(p < 0.05)。ABI与“身体疼痛”(p < 0.01)、“总体健康感知”(p < 0.01)和“心理健康”(p < 0.05)呈正相关。在SF - 36和PDT量表中,“身体角色功能”与“情绪多变”/“神经质”呈负相关(p < 0.05),“社会功能”与“总体活动”呈正相关(p < 0.01)。

结论

客观临床改善是否能提高生活质量主要取决于患者的心理状态:高水平的总体活动有利于生活质量的提高,而神经质特征更可能成为阻碍。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验