调节细胞大小和形状的传感器、换能器和效应器。
Sensors, transducers, and effectors that regulate cell size and shape.
作者信息
Koivusalo Mirkka, Kapus Andras, Grinstein Sergio
机构信息
Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario M5G 1X8, Canada.
出版信息
J Biol Chem. 2009 Mar 13;284(11):6595-9. doi: 10.1074/jbc.R800049200. Epub 2008 Nov 12.
Abstract
Cell volume and shape are stringently regulated. This homeostasis requires the cells to sense their size and shape and to convey this information to effectors that will counteract deformations induced by osmotic or mechanical challenges. The sensors, transducers, and effectors of volume change are the subject of this review.
摘要
细胞体积和形状受到严格调控。这种稳态要求细胞感知其大小和形状，并将此信息传递给效应器，以抵消由渗透或机械挑战引起的变形。体积变化的传感器、换能器和效应器是本综述的主题。
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