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儿童对社区获得性金黄色葡萄球菌感染的抗体反应针对杀白细胞素。

Pediatric antibody response to community-acquired Staphylococcus aureus infection is directed to Panton-Valentine leukocidin.

作者信息

Brown Eric L, Bowden M Gabriela, Bryson Rebecca S, Hulten Kristina G, Bordt Andrea S, Forbes Andrea, Kaplan Sheldon L

机构信息

Center for Infectious Disease, University of Texas School of Public Health, 1200 Herman-Pressler Dr., Houston, TX 77030, USA.

出版信息

Clin Vaccine Immunol. 2009 Jan;16(1):139-41. doi: 10.1128/CVI.00360-08. Epub 2008 Nov 12.

Abstract

We examined the antibody responses of pediatric patients infected with community-associated Staphylococcus aureus isolates. The data show that patients infected with Panton-Valentine leukocidin (PVL)-positive strains developed a dominant immunoglobulin G anti-PVL antibody response that correlates with markers of inflammation.

摘要

我们检测了感染社区获得性金黄色葡萄球菌分离株的儿科患者的抗体反应。数据显示,感染杀白细胞素(PVL)阳性菌株的患者产生了占主导地位的免疫球蛋白G抗PVL抗体反应,该反应与炎症标志物相关。

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