Kheirandish-Gozal Leila, Gozal David
Division of Pediatric Sleep Medicine, Department of Pediatrics, University of Louisville, Louisville, Kentucky, USA.
Curr Opin Pediatr. 2008 Dec;20(6):650-3. doi: 10.1097/MOP.0b013e328316bdb2.
To review some of the inherent problems in defining the diagnosis of pediatric obstructive sleep apnea (OSA) and propose a novel approach to clinical evaluation and referral of habitually snoring children.
OSA has emerged in the last 30 years as a highly prevalent condition in children. However, the diagnostic uncertainties associated with the clinical presentation and physical examination, and changes in the clinical phenotype over time dictated by the escalation of obesity in children, along with the objective difficulties in accessing appropriately equipped sleep laboratories, have led to substantial underrecognition and to implementation of empirically driven treatment interventions for which scientific validity and efficacy remain undefined.
Current tools for the diagnosis of OSA in children are labor-intensive, and onerous, and remain unvalidated. Novel diagnostic approaches linking objective physiological, biological, or both, measures to defined outcomes of pediatric OSA need to be developed and validated to enable wider and earlier recognition of this condition.
回顾定义小儿阻塞性睡眠呼吸暂停(OSA)诊断时存在的一些固有问题,并提出一种针对习惯性打鼾儿童的临床评估和转诊新方法。
在过去30年中,OSA已成为儿童中一种高度普遍的病症。然而,与临床表现和体格检查相关的诊断不确定性,以及儿童肥胖率上升所导致的临床表型随时间的变化,再加上进入配备适当的睡眠实验室存在客观困难,导致该病症未得到充分认识,并导致实施了经验性治疗干预措施,而这些措施的科学有效性和疗效仍不明确。
目前用于诊断儿童OSA的工具既耗费人力又繁琐,且尚未经过验证。需要开发并验证将客观生理、生物学或两者兼有的测量方法与小儿OSA的明确结果相联系的新型诊断方法,以便更广泛、更早地识别这种病症。