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起源于鼻咽外侧壁的小细胞神经内分泌癌。

Small-cell neuroendocrine carcinoma originating from the lateral nasopharyngeal wall.

作者信息

Deviprasad Shetty, Rajeshwari Aroor, Tahir Mohammed, Adarsha T V, Gangadhara Somayaji

机构信息

Department of ENT and Head and Neck Surgery, Yenepoya Medical College, Mangalore, Karnataka, India.

出版信息

Ear Nose Throat J. 2008 Nov;87(11):E1-3.

PMID:19006052
Abstract

A 40-year-old man presented with right-sided nasal blockage and epistaxis of 18 months' duration. Examination revealed a pinkish mass in the right nasal cavity and nasopharynx. Initial biopsy was suggestive of angiofibroma. Complete excision through a lateral rhinotomy approach was performed. The postoperative histopathologic report was suggestive of sinonasal neuroendocrine carcinoma, which was confirmed by immunohistochemistry. To the best of our knowledge, this is the first reported case of sinonasal neuroendocrine carcinoma arising from the lateral wall of the nasopharynx in the English literature. We describe its clinical presentation and management and provide a brief review of the literature.

摘要

一名40岁男性,有持续18个月的右侧鼻塞和鼻出血症状。检查发现右侧鼻腔和鼻咽部有一个粉红色肿物。初步活检提示为血管纤维瘤。通过外侧鼻切开术进行了完整切除。术后组织病理学报告提示为鼻窦神经内分泌癌,免疫组化予以证实。据我们所知,这是英文文献中首例报道的起源于鼻咽部侧壁的鼻窦神经内分泌癌。我们描述了其临床表现和治疗方法,并对文献进行了简要综述。

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1
Small-cell neuroendocrine carcinoma originating from the lateral nasopharyngeal wall.起源于鼻咽外侧壁的小细胞神经内分泌癌。
Ear Nose Throat J. 2008 Nov;87(11):E1-3.
2
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Lateral rhinotomy combined with anterior transantral approach for the treatment of large malignant melanoma of the nasal cavity involving the nasopharynx.外侧鼻切开术联合经前牙槽突入路治疗累及鼻咽部的鼻腔大型恶性黑色素瘤。
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Postirradiated neuroendocrine carcinoma of the sinonasal tract.鼻窦照射后神经内分泌癌
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Mod Pathol. 1997 Aug;10(8):777-84.

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2
Primary Small Cell Neuroendocrine Carcinoma of nasopharynx with metastatic cervical lymph nodes: an exceedingly rare entity with review of literature.鼻咽部原发性小细胞神经内分泌癌伴颈部淋巴结转移:一种极其罕见的实体肿瘤,并进行文献复习。
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Radiat Oncol. 2021 Oct 11;16(1):198. doi: 10.1186/s13014-021-01898-z.
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Small Cell Neuroendocrine Carcinoma: A Rare Nasopharyngeal Malignancy with Aggressive Clinical Course.小细胞神经内分泌癌:一种临床病程侵袭性强的罕见鼻咽恶性肿瘤。
Indian J Otolaryngol Head Neck Surg. 2018 Sep;70(3):454-458. doi: 10.1007/s12070-018-1344-1. Epub 2018 Apr 12.
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