特发性炎性肌病

Idiopathic inflammatory myopathies.

作者信息

Limaye V S, Blumbergs P, Roberts-Thomson P J

机构信息

Rheumatology Department, Royal Adelaide Hospital, University of Adelaide, South Australia, Australia.

出版信息

Intern Med J. 2009 Mar;39(3):179-190. doi: 10.1111/j.1445-5994.2008.01822.x.

DOI:10.1111/j.1445-5994.2008.01822.x

PMID:19006486

Abstract

The idiopathic inflammatory myopathies are a group of systemic autoimmune syndromes characterized by striated muscle inflammation. Here, we discuss the clinical features of this group of conditions and review the recent developments in the understanding of the pathogenesis and immunogenetics of the idiopathic inflammatory myopathies. The role of myositis-specific autoantibodies and their clinical significance and an overview of management are also provided.

摘要

特发性炎性肌病是一组以横纹肌炎症为特征的全身性自身免疫综合征。在此，我们讨论这组疾病的临床特征，并回顾特发性炎性肌病发病机制和免疫遗传学认识方面的最新进展。还介绍了肌炎特异性自身抗体的作用及其临床意义以及治疗概述。