Pandit Anil, Arjyal Amit, Paudyal Buddhi, Campbell James C, Day Jeremy N, Farrar Jeremy J, Basnyat Buddha
Clinical Research, Patan Hospital, Lalitpur, Nepal.
J Travel Med. 2008 Sep-Oct;15(5):364-5. doi: 10.1111/j.1708-8305.2008.00238.x.
A 15-year-old Nepalese boy with fever was thought to have enteric fever and started on cefixime. His blood culture grew Salmonella paratyphoid A. On the sixth day, he developed gastrointestinal bleeding, disseminated intravascular coagulation, and later, acute respiratory distress syndrome. He succumbed to his illness despite treatment in the intensive care unit with ceftriaxone, intravenous fluids, and mechanical ventilation. Salmonella paratyphoid A, for which there is no commercial vaccine, may not be a benign disease as perceived, and cefixime that is recommended for enteric fever may be an ineffective choice.
一名15岁发热的尼泊尔男孩被诊断为伤寒热，并开始使用头孢克肟进行治疗。他的血培养结果显示感染了甲型副伤寒沙门氏菌。第六天，他出现了胃肠道出血、弥散性血管内凝血，随后又出现了急性呼吸窘迫综合征。尽管在重症监护病房接受了头孢曲松、静脉输液和机械通气治疗，他最终还是因病去世。甲型副伤寒沙门氏菌没有商用疫苗，可能并不像人们认为的那样是一种良性疾病，而推荐用于治疗伤寒热的头孢克肟可能是一种无效的选择。
