Woods Christopher W, Murdoch David R, Zimmerman Mark D, Glover William A, Basnyat Buddha, Wolf Leslie, Belbase Ram Hari, Reller L Barth
Duke University Medical Center, Durham, NC, USA.
Trans R Soc Trop Med Hyg. 2006 Nov;100(11):1063-7. doi: 10.1016/j.trstmh.2005.12.011. Epub 2006 May 22.
We performed pulsed-field gel electrophoresis (XbaI) on 114 bloodstream isolates of Salmonella enterica serotype Paratyphi A and S. enterica serotype Typhi collected from febrile patients in Kathmandu, Nepal. Of the 56 S. Paratyphi A isolates, 51 (91%) were indistinguishable, which suggests the emergence of a single clone. In contrast, only 21 (36%) of the 58 S. Typhi isolates exhibited a common genotype, which is consistent with endemic disease from multiple sources.
我们对从尼泊尔加德满都发热患者中分离出的114株甲型副伤寒沙门氏菌和伤寒沙门氏菌进行了脉冲场凝胶电泳（XbaI）分析。在56株甲型副伤寒沙门氏菌分离株中，51株（91%）无法区分，这表明出现了单一克隆。相比之下，58株伤寒沙门氏菌分离株中只有21株（36%）表现出共同的基因型，这与多种来源的地方病一致。
