Lanosa Ximena A, Colombo Jorge A
Unidad de Neurobiología Aplicada, CEMIC, Buenos Aires, Argentina.
Neuron Glia Biol. 2008 Feb;4(1):27-34. doi: 10.1017/S1740925X09000039. Epub 2008 Nov 13.
Cell contact-dependent signaling is a major regulatory mechanism in the organization of developing tissues and in the reorganization (post-injury responses) of specialized tissues in multicellular organisms. In this review we contribute to the further understanding of post-injury recovery processes in adult nervous tissue. We emphasize evidence that supports the involvement of cell contact-inhibition signaling in the cell proliferation, growth and differentiation that occurs during healing and neural reorganization after brain damage.