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N-取代(1,3-噻唑)烷基磺胺衍生物的合成及其杀虫活性

Synthesis and insecticidal activity of N-substituted (1,3-thiazole)alkyl sulfoximine derivatives.

作者信息

Yu Haibo, Qin Zhenfang, Dai Hong, Zhang Xin, Qin Xue, Wang Tingting, Fang Jianxin

机构信息

Research Institute of Elemento-Organic Chemistry, Nankai University, Tianjin, People's Republic of China.

出版信息

J Agric Food Chem. 2008 Dec 10;56(23):11356-60. doi: 10.1021/jf802802g.

Abstract

The N-substituted alkyl sulfoximine derivatives are a new chemical family of neonicotinoid insecticides. We have designed and synthesized 10 (1,3-thiazole)alkyl sulfoximine derivatives. All compounds were identified by (1)H and (13)C nuclear magnetic resonance (NMR), IR, and elemental analyses. Preliminary bioassays indicated that some title compounds exhibited good insecticidal activities at 10 mg/L against Myzus persicae . The relationship between structure and biological activity was also discussed.

摘要

N-取代烷基磺胺肟衍生物是一类新型的新烟碱类杀虫剂。我们设计并合成了10种(1,3-噻唑)烷基磺胺肟衍生物。所有化合物均通过氢核磁共振(¹H NMR)、碳核磁共振(¹³C NMR)、红外光谱(IR)和元素分析进行鉴定。初步生物测定表明,部分目标化合物在10 mg/L浓度下对桃蚜表现出良好的杀虫活性。同时还讨论了结构与生物活性之间的关系。

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