Danila Maria I, Bridges S Louis
Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, 1530 3rd Avenue South, 805 FOT, Birmingham, AL 35294, USA.
Curr Rheumatol Rep. 2008 Dec;10(6):430-5. doi: 10.1007/s11926-008-0070-1.
Systemic necrotizing vasculitis is rare but can have serious sequelae. Despite recent advances in cellular and molecular immunology and genetics, the causes of vasculitic syndromes remain largely undefined. Although mechanisms of blood vessel damage in systemic necrotizing vasculitis are complex, recent studies have provided significant insights.
系统性坏死性血管炎较为罕见，但可产生严重的后遗症。尽管细胞和分子免疫学以及遗传学方面近来有所进展，但血管炎综合征的病因在很大程度上仍不明确。虽然系统性坏死性血管炎中血管损伤的机制很复杂，但最近的研究已提供了重要的见解。
